Macrophage Scavenger Receptor 1 Protein (MSR1) (Myc-DYKDDDDK Tag)
-
- 抗原 See all Macrophage Scavenger Receptor 1 (MSR1) 蛋白
- Macrophage Scavenger Receptor 1 (MSR1)
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This Macrophage Scavenger Receptor 1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human CD204 (transcript variant SR-AII) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MSR1 蛋白
-
Macrophage Scavenger Receptor 1 (MSR1) (AA 77-451) protein (His tag)
MSR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Scavenger Receptor 1 (MSR1) (AA 121-220) protein (GST tag)MSR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Macrophage Scavenger Receptor 1 (MSR1) protein (His tag)MSR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Macrophage Scavenger Receptor 1 (MSR1) protein (Fc Tag)MSR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Macrophage Scavenger Receptor 1 (MSR1) (AA 1-451) protein (Strep Tag)Crystallography grade MSR1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Macrophage Scavenger Receptor 1 (MSR1) (AA 1-458) protein (Strep Tag)Crystallography grade MSR1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Macrophage Scavenger Receptor 1 (MSR1) (AA 77-451) protein (His tag)Crystallography grade MSR1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Scavenger Receptor 1 (MSR1) (AA 79-458) protein (His tag)Crystallography grade MSR1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- Macrophage Scavenger Receptor 1 (MSR1)
- 别名
- CD204 (MSR1 产品)
- 别名
- CD204 Protein, SCARA1 Protein, SR-A Protein, SRA Protein, phSR1 Protein, phSR2 Protein, MRS-A Protein, MSR Protein, MSR-A Protein, SR-AI Protein, SR-AII Protein, Scara1 Protein, Scvr Protein, MSR1 Protein, RGD1564316 Protein, macrophage scavenger receptor 1 Protein, scavenger receptor class A member 5 Protein, MSR1 Protein, Msr1 Protein, SCARA5 Protein
- 背景
- This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
- 分子量
- 39.4 kDa
- NCBI登录号
- NP_002436
-
