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Kallikrein 8 Protein (KLK8) (His tag)

KLK8 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
产品编号 ABIN7534291
发货至: 中国
  • 抗原 See all Kallikrein 8 (KLK8) 蛋白
    Kallikrein 8 (KLK8)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 11
    • 4
    • 3
    资源
    • 6
    • 3
    • 2
    • 2
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    • 1
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    • 1
    HEK-293 Cells
    标记
    This Kallikrein 8 protein is labelled with His tag.
    原理
    Active Recombinant Human Kallikrein-8/KLK8 Protein
    序列
    QEDKVLGGHE CQPHSQPWQA ALFQGQQLLC GGVLVGGNWV LTAAHCKKPK YTVRLGDHSL QNKDGPEQEI PVVQSIPHPC YNSSDVEDHN HDLMLLQLRD QASLGSKVKP ISLADHCTQP GQKCTVSGWG TVTSPRENFP DTLNCAEVKI FPQKKCEDAY PGQITDGMVC AGSSKGADTC QGDSGGPLVC DGALQGITSW GSDPCGRSDK PGVYTNICRY LDWIKKIIGS KG
    特异性
    Gln29-Gly260
    纯度
    > 95 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >44.95 pmol/min/μg.
    Top Product
    Discover our top product KLK8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    Kallikrein 8 (KLK8)
    别名
    Kallikrein-8/KLK8 (KLK8 产品)
    别名
    HNP Protein, NP Protein, NRPN Protein, PRSS19 Protein, TADG14 Protein, bsp1 Protein, KLK8 Protein, BSP1 Protein, Nrpn Protein, Prss19 Protein, kallikrein related peptidase 8 Protein, kallikrein related-peptidase 8 Protein, KLK8 Protein, Klk8 Protein
    背景

    Description: Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein and KLK8, is a secreted protein which belongs to the peptidase S1 family and Kallikrein subfamily. It is a serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Kallikrein-8 / KLK8 is involved in skin desquamation and keratinocyte proliferation and plays a role in the secondary phase of pathogenesis following spinal cord injury. Kallikrein-8 / KLK8 is expressed at high levels in serum, ascites fluid and tumor cytosol of advanced stage ovarian cancer patients and may serve as a marker of ovarian cancer.

    Name: KLK8, HNP, NP, NRPN, PRSS19, TADG14, kallikrein-8,Kallikrein 8,HNP,NP,NRPN,PRSS19,TADG14

    基因ID
    11202
    UniProt
    O60259
    途径
    Complement System
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