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ICAM-3/CD50 Protein (Fc Tag,His tag)

ICAM3 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % by SDS-PAGE. Active
产品编号 ABIN7534560
发货至: 中国
  • 抗原 See all ICAM-3/CD50 (ICAM3) 蛋白
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 12
    • 1
    • 1
    资源
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This ICAM-3/CD50 protein is labelled with Fc Tag,His tag.
    原理
    Active Recombinant Human ICAM-3/CD50 Protein
    序列
    QEFLLRVEPQ NPVLSAGGSL FVNCSTDCPS SEKIALETSL SKELVASGMG WAAFNLSNVT GNSRILCSVY CNGSQITGSS NITVYRLPER VELAPLPPWQ PVGQNFTLRC QVEDGSPRTS LTVVLLRWEE ELSRQPAVEE PAEVTATVLA SRDDHGAPFS CRTELDMQPQ GLGLFVNTSA PRQLRTFVLP VTPPRLVAPR FLEVETSWPV DCTLDGLFPA SEAQVYLALG DQMLNATVMN HGDTLTATAT ATARADQEGA REIVCNVTLG GERREARENL TVFSFLGPIV NLSEPTAHEG STVTVSCMAG ARVQVTLDGV PAAAPGQPAQ LQLNATESDD GRSFFCSATL EVDGEFLHRN SSVQLRVLYG PKIDRATCPQ HLKWKDKTRH VLQCQARGNP YPELRCLKEG SSREVPVGIP FFVNVTHNGT YQCQASSSRG KYTLVVVMDI EAGSSH
    特异性
    Gln30-His485
    纯度
    > 97 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by the ability of the immobilized protein to support the adhesion of THP-1 cells. When cells are added to ICAM-3 coated plates (12.5 μg/mL, 100 μL/well),approximately >50% cells will adhere specifically after 60 minutes at 37 °C.
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    Discover our top product ICAM3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    别名
    ICAM-3/CD50 (ICAM3 产品)
    别名
    CD50 Protein, CDW50 Protein, ICAM-R Protein, ICAM-3 Protein, ICAM3 Protein, intercellular adhesion molecule 3 Protein, ICAM3 Protein, Icam3 Protein
    背景

    Description: This protein is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.

    Name: ICAM3,CD50,CDW50,ICAM-R,ICAM3 / CD50

    基因ID
    3385
    UniProt
    P32942
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