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HHIP Protein (His tag)

HHIP 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % by SDS-PAGE.
产品编号 ABIN7534321
发货至: 中国
  • 抗原 See all HHIP 蛋白
    HHIP (Hedgehog Interacting Protein (HHIP))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 3
    资源
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This HHIP protein is labelled with His tag.
    原理
    Recombinant Human Hedgehog-interacting protein/HHIP Protein
    序列
    FFEGDAKFGE RNEGSGARRR RCLNGNPPKR LKRRDRRMMS QLELLSGGEM LCGGFYPRLS CCLRSDSPGL GRLENKIFSV TNNTECGKLL EEIKCALCSP HSQSLFHSPE REVLERDLVL PLLCKDYCKE FFYTCRGHIP GFLQTTADEF CFYYARKDGG LCFPDFPRKQ VRGPASNYLD QMEEYDKVEE ISRKHKHNCF CIQEVVSGLR QPVGALHSGD GSQRLFILEK EGYVKILTPE GEIFKEPYLD IHKLVQSGIK GGDERGLLSL AFHPNYKKNG KLYVSYTTNQ ERWAIGPHDH ILRVVEYTVS RKNPHQVDLR TARVFLEVAE LHRKHLGGQL LFGPDGFLYI ILGDGMITLD DMEEMDGLSD FTGSVLRLDV DTDMCNVPYS IPRSNPHFNS TNQPPEVFAH GLHDPGRCAV DRHPTDININ LTILCSDSNG KNRSSARILQ IIKGKDYESE PSLLEFKPFS NGPLVGGFVY RGCQSERLYG SYVFGDRNGN FLTLQQSPVT KQWQEKPLCL GTSGSCRGYF SGHILGFGED ELGEVYILSS SKSMTQTHNG KLYKIVDPKR PLMPEECRAT VQPAQTLTSE CSRLCRNGYC TPTGKCCCSP GWEGDFCRTA KCEPACRHGG VCVRPNKCLC KKGYLGPQCE QVD
    特异性
    Phe18-Asp670
    纯度
    > 90 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product HHIP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    HHIP (Hedgehog Interacting Protein (HHIP))
    别名
    Hedgehog-interacting protein/HHIP (HHIP 产品)
    别名
    fd99f01 Protein, wu:fc52e12 Protein, wu:fd99f01 Protein, zgc:153478 Protein, HIP Protein, Xhip Protein, hip Protein, RGD1564108 Protein, Hhip1 Protein, hedgehog interacting protein Protein, hedgehog interacting protein L homeolog Protein, Hedgehog-interacting protein Protein, hhip Protein, HHIP Protein, hhip.L Protein, Hhip Protein
    背景

    Description: Hip (Hedgehog-interacting protein) is a type I transmembrane protein identified for its ability to bind biologically active Sonic Hedgehog.The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The Hip protein is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.

    Name: HHIP,HIP

    基因ID
    64399
    UniProt
    Q96QV1
    途径
    Hedgehog Signaling
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