GFRA2 Protein (His tag)
-
- 抗原 See all GFRA2 蛋白
- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This GFRA2 protein is labelled with His tag.
- 原理
- Active Recombinant Human GDNFR-alpha-2/GFRA2 Protein
- 序列
- SPSSLQGPEL HGWRPPVDCV RANELCAAES NCSSRYRTLR QCLAGRDRNT MLANKECQAA LEVLQESPLY DCRCKRGMKK ELQCLQIYWS IHLGLTEGEE FYEASPYEPV TSRLSDIFRL ASIFSGTGAD PVVSAKSNHC LDAAKACNLN DNCKKLRSSY ISICNREISP TERCNRRKCH KALRQFFDRV PSEYTYRMLF CSCQDQACAE RRRQTILPSC SYEDKEKPNC LDLRGVCRTD HLCRSRLADF HANCRASYQT VTSCPADNYQ ACLGSYAGMI GFDMTPNYVD SSPTGIVVSP WCSCRGSGNM EEECEKFLRD FTENPCLRNA IQAFGNGTDV NVSPKGPSFQ ATQAPRVEKT PSLPDDLSDS TSLGTSVITT CTSVQEQGLK ANNSKELSMC FTELTTNIIP GSNKVIKPNS
- 特异性
- Ser22-Ser441
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized recombinant Human Neurturin at 5 μg/mL (100 μL/well) can bind recombinant Human GFRA2, the EC50 of Human GFRA2 is 1.82 μg/mL.
- Top Product
- Discover our top product GFRA2 蛋白
-
GDNF Family Receptor alpha 2 (GFRA2) (AA 22-444) protein (His tag)
Crystallography grade GFRA2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
GDNF Family Receptor alpha 2 (GFRA2) (AA 22-443) protein (His tag)Crystallography grade GFRA2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) protein (T7 tag,His tag)GFRA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % ELISA, SDS, WB, IP
GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) protein (T7 tag,His tag)GFRA2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % ELISA, SDS, WB, IP
GDNF Family Receptor alpha 2 (GFRA2) (Transcript Variant 2) proteinGFRA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
-
Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
-
- 抗原
- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
- 别名
- GDNFR-alpha-2/GFRA2 (GFRA2 产品)
- 别名
- GDNFRB Protein, NRTNR-ALPHA Protein, NTNRA Protein, RETL2 Protein, TRNR2 Protein, Retl2 Protein, NTNRALPHA Protein, ntnra Protein, retl2 Protein, trnr2 Protein, gdnfrb Protein, nrtnr-alpha Protein, gfra2 Protein, GDNF family receptor alpha 2 Protein, glial cell line derived neurotrophic factor family receptor alpha 2 Protein, GDNF family receptor alpha 2a Protein, GFRA2 Protein, Gfra2 Protein, gfra2 Protein, gfra2a Protein
- 背景
-
Description: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases.
Name: GFRA2,GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2
- 基因ID
- 2675
- UniProt
- O00451
-
