GFRA2 Protein (AA 22-441) (His tag)
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- 抗原 See all GFRA2 蛋白
- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-441
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宿主
- 人
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资源
- 人细胞
- 标记
- This GFRA2 protein is labelled with His tag.
- 原理
- Recombinant Human GDNF Receptor α-2/GFRA2 (C-6His)
- 序列
- SPSSLQGPEL HGWRPPVDCV RANELCAAES NCSSRYRTLR QCLAGRDRNT MLANKECQAA LEVLQESPLY DCRCKRGMKK ELQCLQIYWS IHLGLTEGEE FYEASPYEPV TSRLSDIFRL ASIFSGTGAD PVVSAKSNHC LDAAKACNLN DNCKKLRSSY ISICNREISP TERCNRRKCH KALRQFFDRV PSEYTYRMLF CSCQDQACAE RRRQTILPSC SYEDKEKPNC LDLRGVCRTD HLCRSRLADF HANCRASYQT VTSCPADNYQ ACLGSYAGMI GFDMTPNYVD SSPTGIVVSP WCSCRGSGNM EEECEKFLRD FTENPCLRNA IQAFGNGTDV NVSPKGPSFQ ATQAPRVEKT PSLPDDLSDS TSLGTSVITT CTSVQEQGLK ANNSKELSMC FTELTTNIIP GSNKVIKPNS VDHHHHHH
- 产品特性
- Recombinant Human GDNF Family Receptor alpha-2/GFRA2 produced by transfected human cells is a secreted protein with sequence (Ser22-Ser441) of Human GFRA2 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product GFRA2 蛋白
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GDNF Family Receptor alpha 2 (GFRA2) (AA 22-444) protein (His tag)
Crystallography grade GFRA2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
GDNF Family Receptor alpha 2 (GFRA2) (AA 22-443) protein (His tag)Crystallography grade GFRA2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) protein (T7 tag,His tag)GFRA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % ELISA, SDS, WB, IP
GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) protein (T7 tag,His tag)GFRA2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % ELISA, SDS, WB, IP
GDNF Family Receptor alpha 2 (GFRA2) (Transcript Variant 2) proteinGFRA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
- 别名
- gfr-alpha-2 (GFRA2 产品)
- 别名
- GDNFRB Protein, NRTNR-ALPHA Protein, NTNRA Protein, RETL2 Protein, TRNR2 Protein, Retl2 Protein, NTNRALPHA Protein, ntnra Protein, retl2 Protein, trnr2 Protein, gdnfrb Protein, nrtnr-alpha Protein, gfra2 Protein, GDNF family receptor alpha 2 Protein, glial cell line derived neurotrophic factor family receptor alpha 2 Protein, GDNF family receptor alpha 2a Protein, GFRA2 Protein, Gfra2 Protein, gfra2 Protein, gfra2a Protein
- Sub Type
- Fusionprotein
- 背景
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Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and Neurturin, play key roles in the control of vertebrate neuronal survivial and differentiation. GDNF is a glycosylated, disulfide-bonded homodimer that is distantly related to the TGF superfamily of growth factors. Three receptors for these factors, GFRalpha-1, GFRalpha-2, and GFRalpha-3 have been identified. The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosyl-phosphoinositol linkage. Both GFRalpha-1 and GFRalpha-2 have been shown to mediate the GDNF-dependent and Neurturin-dependent phosphorylation and activation of the tyrosine kinase Ret. GFR-3 is expressed only during development. GFRalpha-2 binds Neurturin and mediates activation of RET receptor tyrosine kinase by both Neurturin and GDNF.
Alternative Names: GDNF Family Receptor Alpha-2, GDNF Receptor Alpha-2, GDNFR-Alpha-2, GFR-Alpha-2, GDNF Receptor Beta, GDNFR-Beta, Neurturin Receptor Alpha, NRTNR-Alpha, NTNR-Alpha, RET Ligand 2, TGF-Beta-Related Neurotrophic Factor Receptor 2, GFRA2, GDNFRB, RETL2, TRNR2 - 分子量
- 47.79 kDa
- UniProt
- O00451
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