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Azurocidin Protein (His tag)

AZU1 宿主: 人 宿主: HEK-293 Cells Recombinant > 85 % by SDS-PAGE.
产品编号 ABIN7534231
发货至: 中国
  • 抗原 See all Azurocidin (AZU1) 蛋白
    Azurocidin (AZU1) (Azurocidin 1 (AZU1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 1
    资源
    • 1
    • 1
    • 1
    • 1
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    • 1
    HEK-293 Cells
    标记
    This Azurocidin protein is labelled with His tag.
    原理
    Recombinant Human Azurocidin/CAP37/AZU1 Protein
    序列
    IVGGRKARPR QFPFLASIQN QGRHFCGGAL IHARFVMTAA SCFQSQNPGV STVVLGAYDL RRRERQSRQT FSISSMSENG YDPQQNLNDL MLLQLDREAN LTSSVTILPL PLQNATVEAG TRCQVAGWGS QRSGGRLSRF PRFVNVTVTP EDQCRPNNVC TGVLTRRGGI CNGDGGTPLV CEGLAHGVAS FSLGPCGRGP DFFTRVALFR DWIDGVLNNP GPGP
    特异性
    Ile27-Pro250
    纯度
    > 85 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.1 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product AZU1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    Azurocidin (AZU1) (Azurocidin 1 (AZU1))
    别名
    Azurocidin/CAP37/AZU1 (AZU1 产品)
    别名
    AZAMP Protein, AZU Protein, CAP37 Protein, HBP Protein, HUMAZUR Protein, NAZC Protein, AZU1 Protein, Azurocidin Protein, pHBP Protein, azurocidin 1 Protein, azurocidin Protein, AZU1 Protein, CpipJ_CPIJ007384 Protein
    背景

    Description: Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3). Azurocidin has also been identified as a modulator of endothelial permeability. Neutrophils arriving first at sites of inflammation release Azurocidin, which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation. These findings imply that Azurocidin may be a reasonable therapeutic target for a variety of inflammatory disease conditions.

    Name: AZU1,AZAMP,AZU,CAP37,HBP,HUMAZUR,NAZC,hHBP

    基因ID
    566
    UniProt
    P20160
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