Azurocidin Protein (AA 27-250) (His tag)
AZU1
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
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- 抗原 See all Azurocidin (AZU1) 蛋白
- Azurocidin (AZU1) (Azurocidin 1 (AZU1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-250
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宿主
- 人
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资源
- 人细胞
- 标记
- This Azurocidin protein is labelled with His tag.
- 原理
- Recombinant Human Azurocidin/CAP37/HBP (C-6His)
- 序列
- IVGGRKARPR QFPFLASIQN QGRHFCGGAL IHARFVMTAA SCFQSQNPGV STVVLGAYDL RRRERQSRQT FSISSMSENG YDPQQNLNDL MLLQLDREAN LTSSVTILPL PLQNATVEAG TRCQVAGWGS QRSGGRLSRF PRFVNVTVTP EDQCRPNNVC TGVLTRRGGI CNGDGGTPLV CEGLAHGVAS FSLGPCGRGP DFFTRVALFR DWIDGVLNNP GPGPVDHHHH HH
- 产品特性
- Recombinant Human Azurocidin produced by transfected human cells is a secreted protein with sequence (Ile27-Pro250) of Human AZU1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product AZU1 蛋白
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Azurocidin 1 (AZU1) protein (His tag)
AZU1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Azurocidin 1 (AZU1) (AA 1-251) protein (GST tag)AZU1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- Azurocidin (AZU1) (Azurocidin 1 (AZU1))
- 别名
- cap37 (AZU1 产品)
- 别名
- AZAMP Protein, AZU Protein, CAP37 Protein, HBP Protein, HUMAZUR Protein, NAZC Protein, AZU1 Protein, Azurocidin Protein, pHBP Protein, azurocidin 1 Protein, azurocidin Protein, AZU1 Protein, CpipJ_CPIJ007384 Protein
- Sub Type
- Fusionprotein
- 背景
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Azurocidin is an Azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, Neutrophil Elastase (NE), and Proteinase 3 (PR3), however, Azurocidin is not a serine proteinase since the active site serine and histidine residues are replaced. Human Azurocidin together with NE and PR3 are expressed coordinately and are packaged together into azurophil granules during neutrophil differentiation. Azurocidin has been identified as a modulator of endothelial permeability and an important multifunctional inflammatory mediator. Neutrophils arriving first at sites of inflammation release Azurocidin which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation. Azurocidin thus be regarded as a reasonable therapeutic target for a variety of inflammatory disease conditions.
Alternative Names: Azurocidin, Cationic Antimicrobial Protein CAP37, Heparin-Binding Protein, HBP, AZU1 - 分子量
- 25.24 kDa
- UniProt
- P20160
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