ACVR2B Protein (Fc Tag,His tag)
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- 抗原 See all ACVR2B 蛋白
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ACVR2B protein is labelled with Fc Tag,His tag.
- 原理
- Active Recombinant Human Activin RIIB/ACVR2B Protein
- 序列
- SGRGEAETRE CIYYNANWEL ERTNQSGLER CEGEQDKRLH CYASWRNSSG TIELVKKGCW LDDFNCYDRQ ECVATEENPQ VYFCCCEGNF CNERFTHLPE AGGPEVTYEP PPTAPT
- 特异性
- Ser19-Thr134
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- 1.Measured by its binding ability in a functional ELISA.Immobilized Human ACVR2B at 1 μg/mL (100 μL/well) can bind Human BMPRIA with a linear range of 0.5-62.5 ng/mL.|2.Measured by its binding ability in a functional ELISA.Immobilized Human CD105 at 1 μg/mL (100 μL/well) can bind Human ACVR2B with a linear range of 0.49-43.03 ng/mL.
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- Discover our top product ACVR2B 蛋白
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Activin A Receptor, Type IIB (ACVR2B) (AA 161-512) (Active) protein (GST tag)
ACVR2B 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Activin A Receptor, Type IIB (ACVR2B) (AA 1-303) protein (GST tag)ACVR2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IIB (ACVR2B) (AA 21-120) protein (GST tag)ACVR2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IIB (ACVR2B) (Active) protein (His tag,Fc Tag)ACVR2B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Activin A Receptor, Type IIB (ACVR2B) (Active) protein (His tag)ACVR2B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE Active
Activin A Receptor, Type IIB (ACVR2B) (AA 159-512) protein (His tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-137) protein (His tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 159-536) protein (His tag)Crystallography grade ACVR2B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-137) protein (His tag)Crystallography grade ACVR2B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-512) protein (rho-1D4 tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- 抗原
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- 别名
- Activin RIIB/ACVR2B (ACVR2B 产品)
- 别名
- ACVR2B Protein, XAR1 Protein, actr-iib Protein, actriib Protein, ACTRIIB Protein, ActR-IIB Protein, HTX4 Protein, ActRIIB Protein, actr2b Protein, actrIIb Protein, wu:fj97d11 Protein, activin A receptor type 2B Protein, activin A receptor type 2B L homeolog Protein, activin A receptor type 2Ba Protein, activin receptor IIB Protein, ACVR2B Protein, acvr2b Protein, acvr2b.L Protein, Acvr2b Protein, acvr2ba Protein
- 背景
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Description: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Name: ACVR2B,ACTRIIB,ActR-IIB,HTX4
- 基因ID
- 93
- UniProt
- Q13705
- 途径
- Hormone Transport, Cancer Immune Checkpoints
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