IL-21 Protein (AA 1-154) (His tag)
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- 抗原 See all IL-21 (IL21) 蛋白
- IL-21 (IL21) (Interleukin 21 (IL21))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-154
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宿主
- 兔
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资源
- HEK-293 Cells
- 标记
- This IL-21 protein is labelled with His tag.
- 序列
- Met1-Leu154
- 产品特性
- A DNA sequence encoding theRabbit IL21 protein (G1T948) (Met1-Leu154) was expressed with a C-His.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL21 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- IL-21 (IL21) (Interleukin 21 (IL21))
- 别名
- IL21 (IL21 产品)
- 别名
- IL-21 Protein, Za11 Protein, interleukin 21 Protein, IL21 Protein, Il21 Protein
- 背景
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Background: IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).
Synonym: Interleukin-21,IL 21,IL-21
- 分子量
- 14.3 kDa
- UniProt
- G1T948
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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