Interleukin 35 Protein (IL35) (His tag)
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- 抗原 See all Interleukin 35 (IL35) 蛋白
- Interleukin 35 (IL35)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Interleukin 35 protein is labelled with His tag.
- 序列
- Arg21-Lys229&(GGGGS)3&Arg23-Ser219
- 产品特性
- A DNA sequence encoding theHuman IL-35 protein (Q14213&P29459) (Arg21-Lys229&(GGGGS)3&Arg23-Ser219) was expressed with a N-His.
- 纯度
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IL35 蛋白
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Interleukin 35 (IL35) (AA 21-229), (AA 23-219) (Active) protein (His tag)
IL35 宿主: 人 宿主: 大肠杆菌（E. Coli） > 97 % AcA, CC Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Interleukin 35 (IL35)
- 别名
- IL-35 (IL35 产品)
- 背景
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Background: Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Synonym: IL-27 subunit beta,IL-27B,Epstein-Barr virus-induced gene 3 protein,EBV-induced gene 3 protein
- 分子量
- 49.5 kDa
- UniProt
- Q14213, P29459
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