PPARG Protein (AA 234-505) (His tag)
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- 抗原 See all PPARG 蛋白
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- 蛋白类型
- Recombinant
- 产品特性
- AA 234-505
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This PPARG protein is labelled with His tag.
- 序列
- Pro234-Tyr505
- 产品特性
- A DNA sequence encoding theHuman PPARG protein (P37231) (Pro234-Tyr505) was expressed with a N-His.
- 纯度
- >80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PPARG 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- 别名
- PPARG (PPARG 产品)
- 别名
- PPAR gamma Protein, PPARg2 Protein, PPARG Protein, Nr1c3 Protein, PPAR-gamma Protein, PPAR-gamma2 Protein, PPARgamma Protein, PPARgamma2 Protein, NR1C3 Protein, CIMT1 Protein, GLM1 Protein, PPARG1 Protein, PPARG2 Protein, xPPAR-gamma Protein, PPAR-GAMMA Protein, PPARGAMMA Protein, peroxisome proliferator-activated receptor gamma Protein, peroxisome proliferator activated receptor gamma Protein, peroxisome proliferator activated receptor gamma L homeolog Protein, PPARG Protein, Pparg Protein, pparg.L Protein
- 背景
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Background: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels.
Synonym: PPAR-gamma,Nuclear receptor subfamily 1 group C member 3,PPAR-γ
- 分子量
- 28 kDa
- UniProt
- P37231
- 途径
- MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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