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TDGF1 Protein (AA 31-172) (His tag)

TDGF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7504538
发货至: 中国
  • 抗原 See all TDGF1 蛋白
    TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))
    蛋白类型
    Recombinant
    产品特性
    AA 31-172
    宿主
    • 8
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This TDGF1 protein is labelled with His tag.
    原理
    Human TDGF1/Cripto Protein
    序列
    Leu31-Thr172
    产品特性
    Recombinant Human TDGF1/Cripto Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-Thr172.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TDGF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))
    别名
    TDGF1 (TDGF1 产品)
    别名
    CR Protein, CRGF Protein, CRIPTO Protein, CR1 Protein, cripto Protein, cb85 Protein, tdgf1 Protein, wu:fe01d04 Protein, zgc:109829 Protein, Cripto-1 Protein, cr1 Protein, cr1a Protein, frl-1 Protein, frl1 Protein, xcr1 Protein, TDGF1 Protein, tdgf3 Protein, cripto-3 Protein, teratocarcinoma-derived growth factor 1 Protein, teratocarcinoma-derived growth factor 1, member 3 L homeolog Protein, teratocarcinoma-derived growth factor 1, member 1 Protein, TDGF1 Protein, Tdgf1 Protein, tdgf1 Protein, tdgf1.3.L Protein, tdgf1.1 Protein
    背景
    TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involved in the reprogramming of differentiated tumor cells into cancer stem cells through the induction of an EMT program.
    分子量
    16.92 kDa. Due to glycosylation, the protein migrates to 23-30 kDa based on Tris-Bis PAGE result.
    UniProt
    P13385
    途径
    EGFR Signaling Pathway
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