Osteomodulin Protein (OMD) (AA 21-421) (His tag)
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- 抗原 See all Osteomodulin (OMD) 蛋白
- Osteomodulin (OMD)
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-421
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Osteomodulin protein is labelled with His tag.
- 原理
- Human Osteomodulin Protein
- 序列
- Gln21-Glu421
- 产品特性
- Recombinant Human Osteomodulin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln21-Glu421.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product OMD 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Osteomodulin (OMD)
- 别名
- Osteomodulin (OMD 产品)
- 别名
- si:ch211-103f16.5 Protein, OMD Protein, OSAD Protein, SLRR2C Protein, osteomodulin Protein, omd Protein, OMD Protein, Omd Protein
- 背景
- Osteomodulin (OMD) is a member of the small leucine-rich repeat proteoglycan family, which is involved in the organization of the extracellular matrix. OMD is located in bone tissue and is reportedly important for bone mineralization. Mechanistically, OMD could bind to BMP2 via its terminal leucine-rich repeats and formed complexes with BMP2 and its membrane receptors, thus promoting BMP/SMAD signal transduction. In addition, OMD was a putative target gene of SMAD4, which plays a pivotal role in this pathway.
- 分子量
- 48.25 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q99983
- 途径
- Glycosaminoglycan Metabolic Process
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