电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Osteomodulin Protein (OMD) (His tag)

OMD 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
产品编号 ABIN7320274
发货至: 中国
  • 抗原 See all Osteomodulin (OMD) 蛋白
    Osteomodulin (OMD)
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    • 1
    • 1
    小鼠
    资源
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Osteomodulin protein is labelled with His tag.
    原理
    Recombinant Mouse Osteomodulin/OMD Protein (His Tag)
    序列
    Met 1-Ile 423
    产品特性
    A DNA sequence encoding the mouse OMD (NP_036180.1) (Met 1-Ile 423) precusor was expressed, with a C-terminal polyhistidine tag.
    纯度
    > 96 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product OMD 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Osteomodulin (OMD)
    别名
    Osteomodulin/OMD (OMD 产品)
    别名
    si:ch211-103f16.5 Protein, OMD Protein, OSAD Protein, SLRR2C Protein, osteomodulin Protein, omd Protein, OMD Protein, Omd Protein
    背景

    Background: Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein which belongs to the small leucine-rich proteoglycan (SLRP) family and Class II subfamily. SLRP family proteins are normally found in extracellular matrices, but Osteomodulin is the only member restricted to mineralized tissues. Osteomodulin is primarily expressed by osteoblasts and might have a role in regulation of mineralization. In bone OSAD has been localized in primary spongiosa within the bovine fetal rib growth plate. Moreover, in situ hybridization has shown expression of OSAD in osteoblasts close to the cartilage and bone border in the growth plate of rat femur. OSAD may play an important role during tooth development and biomineralization of dentin. Osteomodulin is a cell binding keratan sulfate proteoglycan which was recently isolated from mineralized bovine bone and subsequently cloned and sequenced. Osteomodulin may be implicated in biomineralization processes. It has a function in binding of osteoblasts via the alpha (V) beta (3)-integrin. It is likely that Osteomodulin is an osteoblast maturation marker that is induced by osteoclast activity. Osteomodulin is also an early marker for terminally differentiated matrix producing osteoblasts.

    Synonym: OSAD,SLRR2C

    分子量
    48.8 kDa
    NCBI登录号
    NP_036180
    途径
    Glycosaminoglycan Metabolic Process
You are here: