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Oncostatin M Protein (OSM) (AA 27-221) (His tag)

OSM 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7504490
发货至: 中国
  • 抗原 See all Oncostatin M (OSM) 蛋白
    Oncostatin M (OSM)
    蛋白类型
    Recombinant
    产品特性
    AA 27-221
    宿主
    • 25
    • 7
    • 4
    • 3
    • 1
    Cynomolgus
    资源
    • 21
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This Oncostatin M protein is labelled with His tag.
    原理
    Cynomolgus Oncostatin M/OSM Protein
    序列
    Ala27-Arg221
    产品特性
    Recombinant Cynomolgus Oncostatin M/OSM Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala27-Arg221.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product OSM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Oncostatin M (OSM)
    别名
    Oncostatin M (OSM 产品)
    别名
    OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
    背景
    OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
    分子量
    23.31 kDa. Due to glycosylation, the protein migrates to 27-50 kDa based on Tris-Bis PAGE result.
    NCBI登录号
    XP_045219762
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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