Oncostatin M Protein (OSM) (AA 27-221) (His tag)
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- 抗原 See all Oncostatin M (OSM) 蛋白
- Oncostatin M (OSM)
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-221
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This Oncostatin M protein is labelled with His tag.
- 原理
- Cynomolgus Oncostatin M/OSM Protein
- 序列
- Ala27-Arg221
- 产品特性
- Recombinant Cynomolgus Oncostatin M/OSM Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala27-Arg221.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product OSM 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Oncostatin M (OSM)
- 别名
- Oncostatin M (OSM 产品)
- 别名
- OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
- 背景
- OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
- 分子量
- 23.31 kDa. Due to glycosylation, the protein migrates to 27-50 kDa based on Tris-Bis PAGE result.
- NCBI登录号
- XP_045219762
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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