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Oncostatin M Protein (OSM) (AA 26-234) (His tag)

OSM 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667495
发货至: 中国
  • 抗原 See all Oncostatin M (OSM) 蛋白
    Oncostatin M (OSM)
    蛋白类型
    Recombinant
    产品特性
    AA 26-234
    宿主
    • 24
    • 7
    • 4
    • 3
    • 1
    • 1
    资源
    • 20
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Oncostatin M protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    OSM, 26-234aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product OSM 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    储存条件
    4 °C
  • 抗原
    Oncostatin M (OSM)
    别名
    OSM (OSM 产品)
    别名
    OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
    背景
    OSM, also known as Oncostatin M, is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR. Recombinant human OSM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Oncostatin M, MGC20461, Oncostatin M precursor. NCBI no.: NP_065391
    分子量
    25.9 kDa (230aa), confirmed by MALDI-TOF
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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