Oncostatin M Protein (OSM) (AA 26-234) (His tag)
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- 抗原 See all Oncostatin M (OSM) 蛋白
- Oncostatin M (OSM)
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-234
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Oncostatin M protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- OSM, 26-234aa, Human, His tag, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product OSM 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
- 储存条件
- 4 °C
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- 抗原
- Oncostatin M (OSM)
- 别名
- OSM (OSM 产品)
- 别名
- OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
- 背景
- OSM, also known as Oncostatin M, is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR. Recombinant human OSM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Oncostatin M, MGC20461, Oncostatin M precursor. NCBI no.: NP_065391
- 分子量
- 25.9 kDa (230aa), confirmed by MALDI-TOF
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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