ITGAV/ITGB1 Protein (AA 31-992, Heterodimer) (His-Avi Tag)
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- 抗原 See all ITGAV/ITGB1 products
- ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-992, Heterodimer
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ITGAV/ITGB1 protein is labelled with His-Avi Tag.
- 原理
- Human Integrin alpha V beta 1 (ITGAV & ITGB1) Heterodimer Protein
- 序列
- Phe31-Val992 (ITGAV) acidic tail & Gln21-Asp728 (ITGB1) basic tail
- 特异性
- Uni-Prot: P06756-1 (ITGAV), P05556-1 (ITGB1)
- 产品特性
- Recombinant Human Integrin alpha V beta 1 (ITGAV & ITGB1) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992 (ITGAV) acidic tail & Gln21-Asp728 (ITGB1) basic tail.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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Integrin alpha V + beta 1 (ITGAV/ITGB1) (AA 31-992) protein (His tag)
ITGAV/ITGB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Integrin alpha V + beta 1 (ITGAV/ITGB1) (AA 31-992) (Active) proteinITGAV/ITGB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Integrin alpha V + beta 1 (ITGAV/ITGB1) (AA 31-992) (Active) protein (His tag,AVI tag,Biotin)ITGAV/ITGB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
- 别名
- Integrin alpha V beta 1 (ITGAV/ITGB1 产品)
- 背景
- Integrins are transmembrane heterodimeric receptors that contribute to diverse biological functions and play a conserved role in mediating cell adhesion to fixed extracellular ligands and in the maintenance of tissue integrity. αVβ1 is the major integrin on several different primary fibroblasts responsible for binding to TGFb1 LAP and for mediating activation of latent TGFb by these cells.
- 分子量
- 114 kDa (ITGAV) and 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-160 kDa (ITGAV) and 100-120 kDa (ITGB1) based on Tris-Bis PAGE result.
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