ITGAV/ITGB1 Protein (AA 31-992) (His tag,AVI tag,Biotin)
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- 抗原 See all ITGAV/ITGB1 products
- ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 31-992
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ITGAV/ITGB1 protein is labelled with His tag,AVI tag,Biotin.
- 序列
- AA 31-992
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Integrin alpha V + beta 1 (ITGAV/ITGB1) (AA 31-992) protein (His tag)
ITGAV/ITGB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Integrin alpha V + beta 1 (ITGAV/ITGB1) (AA 31-992) (Active) proteinITGAV/ITGB1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 150 mM NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
- 别名
- Integrin alpha V beta 1 (ITGAV/ITGB1 产品)
- 背景
- Integrin alpha-5/beta-1 is a receptor for ibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-V/beta-1 is also a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition.
- 分子量
- 114.7 kDa (ITGAV) & 83.7 kDa (ITGB1)
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