NGFB 蛋白
Quick Overview for NGFB 蛋白 (ABIN7489071)
抗原
See all NGFB 蛋白蛋白类型
宿主
资源
纯度
质量等级
-
-
原理
- ActiveMax® Mouse Beta-NGF Protein, Tag Free (MALS verified)
-
序列
- Ser 122 - Gly 241
-
产品特性
- ActiveMax® Mouse Beta-NGF Protein, Tag Free is expressed from human 293 cells (HEK293). It contains AA Ser 122 - Gly 241 (Accession # P01139).
-
内毒素水平
- 0.1 EU per μg
-
-
-
-
说明
-
This protein carries no "tag". The protein has a calculated MW of 13.5 kDa. The protein migrates as <14 kDa under reducing (R) condition (SDS-PAGE).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 20 mM NaAC, 150 mM NaCl, pH 5.5
-
储存条件
- -20 °C
-
储存方法
- -20°C
-
-
- NGFB (Nerve Growth Factor beta (NGFB))
-
别名
- Beta-NGF
-
背景
- Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.
-
分子量
- 13.5 kDa
-
途径
- NF-kappaB Signaling, RTK signaling, Regulation of Cell Size
抗原
-