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NGFB 蛋白

This Recombinant NGFB protein is expressed in HEK-293 Cells.
产品编号 ABIN7489071
发货至: 中国

Quick Overview for NGFB 蛋白 (ABIN7489071)

抗原

See all NGFB 蛋白
NGFB (Nerve Growth Factor beta (NGFB))

蛋白类型

Recombinant

宿主

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小鼠

资源

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HEK-293 Cells

纯度

95 %

质量等级

MALS verified
  • 原理

    ActiveMax® Mouse Beta-NGF Protein, Tag Free (MALS verified)

    序列

    Ser 122 - Gly 241

    产品特性

    ActiveMax® Mouse Beta-NGF Protein, Tag Free is expressed from human 293 cells (HEK293). It contains AA Ser 122 - Gly 241 (Accession # P01139).

    内毒素水平

    0.1 EU per μg
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  • 说明

    This protein carries no "tag". The protein has a calculated MW of 13.5 kDa. The protein migrates as <14 kDa under reducing (R) condition (SDS-PAGE).

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    20 mM NaAC, 150 mM NaCl, pH 5.5

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    NGFB (Nerve Growth Factor beta (NGFB))

    别名

    Beta-NGF

    背景

    Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.

    分子量

    13.5 kDa

    途径

    NF-kappaB Signaling, RTK signaling, Regulation of Cell Size
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