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Prokineticin Receptor 1 Protein (PROKR1)

PROKR1 宿主: 人 宿主: HEK-293 Cells Synthetic
产品编号 ABIN7491713
发货至: 中国
  • 抗原 See all Prokineticin Receptor 1 (PROKR1) 蛋白
    Prokineticin Receptor 1 (PROKR1)
    蛋白类型
    Synthetic
    宿主
    • 4
    • 3
    • 2
    • 2
    资源
    • 7
    • 2
    • 2
    HEK-293 Cells
    原理
    Human PROKR1 full length protein-synthetic nanodisc
    产品特性
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product PROKR1 蛋白
  • 应用备注
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    说明

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Prokineticin Receptor 1 (PROKR1)
    别名
    PROKR1 (PROKR1 产品)
    别名
    EG-VEGFR1 Protein, Gpr73 Protein, Pkr1 Protein, GPR73 Protein, GPR73a Protein, PKR1 Protein, ZAQ Protein, PROKR1 Protein, prokineticin receptor 1 Protein, Prokr1 Protein, PROKR1 Protein
    背景
    GPR73, GPR73a, PK-R1, PKR1, ZAQ
    Description: This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]
    分子量
    The human full length PROKR1 protein has a MW of 44.6 kDa
    UniProt
    Q8TCW9
    途径
    Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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