CCR7 蛋白
CCR7
宿主: 人
宿主: HEK-293 Cells
Synthetic
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- 抗原 See all CCR7 蛋白
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- 蛋白类型
- Synthetic
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CCR7 full length protein-synthetic nanodisc
- 产品特性
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CCR7 蛋白
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Chemokine (C-C Motif) Receptor 7 (CCR7) protein (Myc-DYKDDDDK Tag)
CCR7 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- 说明
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- 别名
- CCR7 (CCR7 产品)
- 别名
- zgc:165629 Protein, ccr7-a Protein, CD197 Protein, Cdw197 Protein, Cmkbr7 Protein, EBI1 Protein, Ebi1h Protein, BLR2 Protein, CDw197 Protein, CMKBR7 Protein, chemokine (C-C motif) receptor 7 Protein, C-C motif chemokine receptor 7 Protein, C-C motif chemokine receptor 7 L homeolog Protein, ccr7 Protein, CCR7 Protein, ccr7.L Protein, Ccr7 Protein
- 背景
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BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
Description: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] - 分子量
- The human full length CCR7 protein has a MW of 42.9 kDa
- UniProt
- P32248
- 途径
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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