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CCR7 Protein (Fc Tag)

CCR7 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN6964145
发货至: 中国
  • 抗原 See all CCR7 蛋白
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 3
    • 1
    资源
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This CCR7 protein is labelled with Fc Tag.
    原理
    Recombinant Human CCR7 with C-terminal human Fc tag
    特异性
    CCR7 (Glu25-Trp59) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CCR7 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    别名
    CCR7 (CCR7 产品)
    别名
    zgc:165629 Protein, ccr7-a Protein, CD197 Protein, Cdw197 Protein, Cmkbr7 Protein, EBI1 Protein, Ebi1h Protein, BLR2 Protein, CDw197 Protein, CMKBR7 Protein, chemokine (C-C motif) receptor 7 Protein, C-C motif chemokine receptor 7 Protein, C-C motif chemokine receptor 7 L homeolog Protein, ccr7 Protein, CCR7 Protein, ccr7.L Protein, Ccr7 Protein
    背景
    Synonymes: BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
    Description: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
    分子量
    predicted molecular mass of 30.2 kDa after removal of the signal peptide. The apparent molecular mass of CCR7-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P32248
    途径
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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