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GIPR Protein (Fc Tag)

GIPR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491455
发货至: 中国
  • 抗原 See all GIPR 蛋白
    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 2
    资源
    • 4
    • 1
    HEK-293 Cells
    标记
    This GIPR protein is labelled with Fc Tag.
    原理
    Recombinant Human GIPR Protein with C-terminal human Fc tag
    特异性
    GIPR (Arg22-Gln138) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product GIPR 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
    别名
    GIPR (GIPR 产品)
    别名
    GIPR Protein, PGQTL2 Protein, GIP-R Protein, Gm1081 Protein, Gm160 Protein, Gippr Protein, RATGIPPR Protein, gastric inhibitory polypeptide receptor Protein, glucagon receptor Protein, GIPR Protein, LOC100303705 Protein, Gipr Protein
    背景
    PGQTL2
    Description: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
    分子量
    predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of GIPR-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P48546
    途径
    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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