BMPR1A
宿主: 犬
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
限制
仅限研究用
状态
Lyophilized
缓冲液
sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
储存条件
-20 °C,-80 °C
储存方法
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
有效期
12 months
抗原
BMPR1A
(Bone Morphogenetic Protein Receptor 1A (BMPR1A))
10q23del Protein, ACVRLK3 Protein, ALK3 Protein, CD292 Protein, SKR5 Protein, 1110037I22Rik Protein, AU045487 Protein, BMPR-IA Protein, Bmpr Protein, BMPR-1 Protein, BRK-1 Protein, BMPR1A Protein, acvrlk3 Protein, alk-3 Protein, alk3 Protein, cd292 Protein, skr5 Protein, BR1a Protein, alk3tr Protein, bmpr1a Protein, zgc:136731 Protein, wu:fe05b06 Protein, wu:fe06e10 Protein, zgc:92227 Protein, bone morphogenetic protein receptor type 1A Protein, bone morphogenetic protein receptor, type 1A Protein, bone morphogenetic protein receptor type 1A S homeolog Protein, bone morphogenetic protein receptor, type IAa Protein, bone morphogenetic protein receptor, type IAb Protein, BMPR1A Protein, Bmpr1a Protein, bmpr1a Protein, bmpr1a.S Protein, bmpr1aa Protein, bmpr1ab Protein
背景
ACVRLK3, ALK3, CD292, SKR5The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
分子量
predicted molecular mass of 40.3 kDa after removal of the signal peptide. The apparent molecular mass of BMPR1A-hFc is 35-70 kDa due to glycosylation.