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BMPR1A Protein (His tag,Fc Tag)

BMPR1A 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320751
发货至: 中国
  • 抗原 See all BMPR1A 蛋白
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    蛋白类型
    Recombinant
    宿主
    • 24
    • 7
    • 2
    • 1
    • 1
    小鼠
    资源
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This BMPR1A protein is labelled with His tag,Fc Tag.
    原理
    Recombinant Mouse BMPRIA/ALK-3 Protein (Fc & His Tag)
    序列
    Gln24-Arg152
    产品特性
    Recombinant Mouse Bone Morphogenetic Protein Receptor Type IA/Activin Receptor-like Kinase 3 is produced by our Mammalian expression system and the target gene encoding Gln24-Arg152 is expressed with a Fc, 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product BMPR1A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    别名
    BMPRIA/ALK-3 (BMPR1A 产品)
    别名
    10q23del Protein, ACVRLK3 Protein, ALK3 Protein, CD292 Protein, SKR5 Protein, 1110037I22Rik Protein, AU045487 Protein, BMPR-IA Protein, Bmpr Protein, BMPR-1 Protein, BRK-1 Protein, BMPR1A Protein, acvrlk3 Protein, alk-3 Protein, alk3 Protein, cd292 Protein, skr5 Protein, BR1a Protein, alk3tr Protein, bmpr1a Protein, zgc:136731 Protein, wu:fe05b06 Protein, wu:fe06e10 Protein, zgc:92227 Protein, bone morphogenetic protein receptor type 1A Protein, bone morphogenetic protein receptor, type 1A Protein, bone morphogenetic protein receptor type 1A S homeolog Protein, bone morphogenetic protein receptor, type IAa Protein, bone morphogenetic protein receptor, type IAb Protein, BMPR1A Protein, Bmpr1a Protein, bmpr1a Protein, bmpr1a.S Protein, bmpr1aa Protein, bmpr1ab Protein
    背景

    Background: ALK-3 is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. The BMP receptors consists of the type I receptors BMPR1A and BMPR1B and the type I I receptor BMPR2. Seven known type I serine/threonine kinases and five mammalian type II serine/threonine kinase receptors function in TGF-beta superfamily signal transduction. The downstream molecules of the type I BMP receptors include the Smad (Smad1, 5 and 8) proteins that are phosphorylated in a ligand-dependent manner, and relay the BMP signal from the receptors to target genes in the nucleus. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. ALK-3 contains a GS domain and a protein kinase domain. ALK-3 is widely expressed. Defects in BMPR1A gene are a cause of a significant proportion of cases of Juvenile polyposis syndrome (JPS).

    Synonym: ALK-3,Bone morphogenetic protein receptor type-1A,BMP type-1A receptor,BMPR-1A,Activin receptor-like kinase 3,BMP-2/BMP-4 receptor,Serine/threonine-protein kinase receptor R5,SKR5,CD292,Acvrlk3,Bmpr,BMPR-IA

    分子量
    42.2 kDa
    UniProt
    P36895
    途径
    Stem Cell Maintenance
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