CD84 Protein (CD84) (Fc Tag)
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- 抗原 See all CD84 蛋白
- CD84
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CD84 protein is labelled with Fc Tag.
- 原理
- Recombinant mouse SLAMF5 protein with C-terminal human Fc tag
- 特异性
- Mouse SLAMF5 (Lys22-Val221) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD84 蛋白
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CD84 (CD84) (AA 22-225) protein (His-Avi Tag)
CD84 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD84 (CD84) protein (His tag)CD84 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
CD84 (CD84) protein (mFc-His Tag)CD84 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD84 (CD84) (AA 1-328) protein (GST tag)CD84 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD84 (CD84) (AA 22-121) protein (GST tag)CD84 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD84 (CD84) (Active) protein (His tag)CD84 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
CD84 (CD84) (AA 22-225) protein (His tag)Crystallography grade CD84 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD84 (CD84) (AA 22-221) protein (His tag)Crystallography grade CD84 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD84 (CD84) (AA 22-345) protein (rho-1D4 tag)Crystallography grade CD84 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD84 (CD84) (AA 22-329) protein (rho-1D4 tag)Crystallography grade CD84 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CD84
- 别名
- SLAMF5 (CD84 产品)
- 别名
- RGD1564553 Protein, A130013D22Rik Protein, CDw84 Protein, SLAMF5 Protein, LY9B Protein, hCD84 Protein, mCD84 Protein, CD84 molecule Protein, CD84 antigen Protein, Cd84 Protein, CD84 Protein
- 背景
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SLAM family member 5, CD84
Description: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2 (PubMed:20962259). Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B (PubMed:20962259). Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells (By similarity). Required for a prolonged T-cell:B-cell contact, optimal T follicular helper function, and germinal center formation (PubMed:20153220). In germinal centers involved in maintaining B cell tolerance and in preventing autoimmunity (PubMed:25801429). In mast cells negatively regulates high affinity immunoglobulin epsilon receptor signaling, independent of SH2D1A and SH2D1B but implicating FES and PTPN6/SHP-1 (By similarity). In macrophages enhances LPS-induced MAPK phosphorylation and NF-kappaB activation and modulates LPS-induced cytokine secretion, involving ITSM 2 (PubMed:20628063). Positively regulates macroautophagy in primary dendritic cells via stabilization of IRF8, inhibits TRIM21-mediated proteasomal degradation of IRF8 (By similarity).[UniProtKB/Swiss-Prot Function] - 分子量
- predicted molecular mass of 48.7 kDa after removal of the signal peptide. The apparent molecular mass of mSLAMF5-hFc is 55-70 kDa due to glycosylation.
- UniProt
- Q9UIB8
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