CD84 Protein (CD84) (His tag)
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Quick Overview for CD84 Protein (CD84) (His tag) (ABIN7320156)
抗原
See all CD84 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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标记
- This CD84 protein is labelled with His tag.
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原理
- Recombinant Mouse SLAMF5/CD84 Protein (His Tag)
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序列
- Met 1-Val 221
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产品特性
- A DNA sequence encoding the mouse CD84 isoform 1 (Q18PI6-1) extracellular domain (Met 1-Val 221) was expressed, with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to bind biotinylated recombinant human SH2D1A in a functional ELISA.
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CD84 (CD84) (AA 22-225) (Active) protein (His-Avi Tag)
CD84 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD84 (CD84) (AA 22-225) protein (His tag,mFc Tag)CD84 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD84 (CD84) (AA 22-221) protein (Fc Tag)CD84 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD84 (CD84) (AA 22-225) protein (His tag)CD84 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS
CD84 (CD84) (AA 22-223) protein (His tag)CD84 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
CD84 (CD84) (AA 1-328) protein (GST tag)CD84 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD84
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别名
- SLAMF5/CD84
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背景
- CD84,CD84 antigen,CD84 Molecule,Cd84,Leukocyte differentiation antigen CD84,Ly-9B,SLAM family member 5,SLAMF5,Signaling lymphocytic activation molecule 5,The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
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分子量
- 24 kDa
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基因ID
- 12523
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UniProt
- Q18PI6
抗原
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