B4GALT1 Protein (Fc Tag)
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- 抗原 See all B4GALT1 蛋白
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This B4GALT1 protein is labelled with Fc Tag.
- 原理
- Recombinant human B4GALT1 Protein with N-terminal Human Fc tag
- 特异性
- HFc (Glu99-Ala330) B4GALT1 (Arg45-Ser398)
- 产品特性
- Extracellular Domain Protein
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product B4GALT1 蛋白
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UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (AA 44-153) protein (GST tag)
B4GALT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) protein (His tag)B4GALT1 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (AA 1-24) protein (GST tag)B4GALT1 宿主: Cow 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
- 别名
- B4GALT1 (B4GALT1 产品)
- 别名
- B4GAL-T1 Protein, CDG2D Protein, GGTB2 Protein, GT1 Protein, GTB Protein, beta4Gal-T1 Protein, B-1,4-GalT Protein, B-1,4-GalT1 Protein, GalT Protein, Ggtb Protein, Ggtb2 Protein, b4Gal-T1 Protein, beta-1,4-GalT Protein, beta-1,4-GalT1 Protein, beta-1,4-galactosyltransferase 1 Protein, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 Protein, B4GALT1 Protein, B4galt1 Protein
- 背景
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GGTB2, Beta4Gal-T1, b4Gal-T1, Nal synthase
Description: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose D-glucose UDP lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase. [provided by RefSeq, Jul 2008] - 分子量
- predicted molecular mass of 65.4 kDa after removal of the signal peptide. The apparent molecular mass of hFc-B4GALT1 is 55-70 kDa due to glycosylation.
- UniProt
- P15291
- 途径
- Glycosaminoglycan Metabolic Process
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