B4GALT1 Protein (His tag)
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- 抗原 See all B4GALT1 蛋白
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This B4GALT1 protein is labelled with His tag.
- 原理
- Recombinant Human B4GALT1 (C-6His)
- 序列
- Gly44-Ser398(Tyr285Leu)
- 产品特性
- Recombinant Human Beta-1,4-galactosyltransferase 1 is produced by our Mammalian expression system and the target gene encoding Gly44-Ser398(Tyr285Leu) is expressed with a 6His tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product B4GALT1 蛋白
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UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (AA 44-153) protein (GST tag)
B4GALT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (AA 1-24) protein (GST tag)B4GALT1 宿主: Cow 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
- 别名
- B4GALT1 (B4GALT1 产品)
- 别名
- B4GAL-T1 Protein, CDG2D Protein, GGTB2 Protein, GT1 Protein, GTB Protein, beta4Gal-T1 Protein, B-1,4-GalT Protein, B-1,4-GalT1 Protein, GalT Protein, Ggtb Protein, Ggtb2 Protein, b4Gal-T1 Protein, beta-1,4-GalT Protein, beta-1,4-GalT1 Protein, beta-1,4-galactosyltransferase 1 Protein, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 Protein, B4GALT1 Protein, B4galt1 Protein
- 背景
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Background: Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. By sequence similarity, the beta 4GalTs form four groups: beta 4GalT1 and beta 4GalT2, beta 4GalT3 and beta 4GalT4, beta 4GalT5 and beta 4GalT6, and beta 4GalT7. beta 4GalT1 is unique among the seven enzymes because it can be expressed either as membrane associated form or secreted form. The secreted form is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha -lactalbumin to catalyze the synthesis of lactose. The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix. Defects in beta 4GalT1 are the cause of congenital disorder of glycosylation type 2D (CDG2D) .
Synonym: 1,4- galactosyltransferase, polypeptide 1, B4GalT1, B4GAL-T1, beta-1,4-galactosyltransferase 1, Beta-1,4-GalTase 1, beta4Gal-T1, betaGlcNAc beta, CDG2D, GT1, GTB
- 分子量
- 40.1 kDa
- UniProt
- P15291
- 途径
- Glycosaminoglycan Metabolic Process
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