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CXCL10 Protein (Fc Tag)

CXCL10 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7490675
发货至: 中国
  • 抗原 See all CXCL10 蛋白
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    蛋白类型
    Recombinant
    宿主
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    资源
    • 23
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CXCL10 protein is labelled with Fc Tag.
    原理
    Recombinant Cynomolgus CXCL10 protein with C-terminal human Fc tag
    特异性
    CXCL10 (Ile22-Pro98) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CXCL10 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    别名
    CXCL10 (CXCL10 产品)
    别名
    CXCL10 Protein, C7 Protein, IFI10 Protein, INP10 Protein, IP-10 Protein, SCYB10 Protein, crg-2 Protein, gIP-10 Protein, mob-1 Protein, CRG-2 Protein, IP10 Protein, Ifi10 Protein, Scyb10 Protein, C-X-C motif chemokine ligand 10 Protein, C-X-C motif chemokine 10 Protein, chemokine (C-X-C motif) ligand 10 Protein, CXCL10 Protein, cxl10 Protein, Cxcl10 Protein
    背景
    Gamma-IP10, IP-10, SCYB10, INP10(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.
    分子量
    predicted molecular mass of 34.8 kDa after removal of the signal peptide.The apparent molecular mass of cCXCL10-hFc is 25-55 kDa due to glycosylation.
    UniProt
    P02778
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