CXCL10 Protein (AA 22-98)
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- 抗原 See all CXCL10 蛋白
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 22-98
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- Cell Migration Assay (CMA)
- 序列
- VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP
- 产品特性
- Recombinant Human CXCL10 (IP-10)
- 内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 6.3 nM determined by Migration Assay in cells expressing recombinant CXCR3
- Top Product
- Discover our top product CXCL10 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- 储存条件
- -20 °C,-80 °C
- 储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - 有效期
- 12 months
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- 抗原
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- 别名
- CXCL10 (IP-10) (CXCL10 产品)
- 别名
- CXCL10 Protein, C7 Protein, IFI10 Protein, INP10 Protein, IP-10 Protein, SCYB10 Protein, crg-2 Protein, gIP-10 Protein, mob-1 Protein, CRG-2 Protein, IP10 Protein, Ifi10 Protein, Scyb10 Protein, C-X-C motif chemokine ligand 10 Protein, C-X-C motif chemokine 10 Protein, chemokine (C-X-C motif) ligand 10 Protein, CXCL10 Protein, cxl10 Protein, Cxcl10 Protein
- 背景
- CXCL10 (IP-10) was originally identified as an IFN-gamma-inducible gene in endothelial, fibroblasts and monocytes cells. IP-10 is considered a member of the CXC chemokine subfamily from its protein sequence which includes the four conserved cysteine residues present in CXC chemokines. IP-10 signals through the CXCR3 receptor to selectively attract Th1 lymphocytes and monocytes. It also has angiostatic and mitogenic properties on vascular smooth muscle cells. A diverse population of cell types rapidly increases transcription of mRNA encoding IP-10, which suggests that gamma-induced protein may be a key mediator of the IFNG/IFN-gamma response.
- 分子量
- 8.646 kDa
- UniProt
- P02778
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