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SARS-CoV-2 Spike Protein (RBD) (Fc Tag)

This Recombinant SARS-CoV-2 Spike protein is expressed in HEK-293 Cells.
产品编号 ABIN7490663
发货至: 中国

Quick Overview for SARS-CoV-2 Spike Protein (RBD) (Fc Tag) (ABIN7490663)

抗原

See all SARS-CoV-2 Spike 蛋白
SARS-CoV-2 Spike

蛋白类型

Recombinant

宿主

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SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

资源

  • 136
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HEK-293 Cells

纯度

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    RBD

    标记

    This SARS-CoV-2 Spike protein is labelled with Fc Tag.

    原理

    Recombinant SARS-CoV-2 RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) protein with C-terminal human Fc tag

    特异性

    S protein RBD (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) (Arg319-Phe541) hFc (Glu99-Ala330)

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    SARS-CoV-2 Spike

    物质类

    Viral Protein

    背景

    SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.

    分子量

    predicted molecular mass of 51.2 kDa after removal of the signal peptide.The apparent molecular mass of RBD(G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H)-hFc is 55-70 kDa due to glycosylation.

    UniProt

    P0DTC2
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