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IL-37 Protein (AA 27-192)

IL37 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7454154
发货至: 中国
  • 抗原 See all IL-37 (IL37) 蛋白
    IL-37 (IL37) (Interleukin 37 (IL37))
    蛋白类型
    Recombinant
    产品特性
    AA 27-192
    宿主
    资源
    • 7
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Human IL-37 Protein
    序列
    Lys27-Asp192
    产品特性
    Recombinant Human IL-37 Protein is expressed from E.coli without tag.It contains Lys27-Asp192.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.12 μM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL37 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in 20 mM PBS, 2 mM DTT ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存液
    Dithiothreitol (DTT)
    注意事项
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL-37 (IL37) (Interleukin 37 (IL37))
    别名
    IL-37 (IL37 产品)
    别名
    FIL1 Protein, FIL1(ZETA) Protein, FIL1Z Protein, IL-1F7 Protein, IL-1H Protein, IL-1H4 Protein, IL-1RP1 Protein, IL-37 Protein, IL1F7 Protein, IL1H4 Protein, IL1RP1 Protein, interleukin 37 Protein, IL37 Protein
    背景
    IL-37 is a unique member of the IL-1 family of cytokines, which functions as a natural suppressor of inflammatory and immune responses. Immune and non-immune cells produce IL-37 precursor following pro-inflammatory stimuli. Following activating cleavage by caspase-1, mature IL-37 translocates to the nucleus, where it suppresses transcription of pro-inflammatory genes.
    分子量
    18.55 kDa same as Tris-Bis PAGE result.
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