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IFNA Protein (AA 27-243) (His tag)

IFNA 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7454144
发货至: 中国
  • 抗原 See all IFNA 蛋白
    IFNA (Interferon alpha (IFNA))
    蛋白类型
    Recombinant
    产品特性
    AA 27-243
    宿主
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    资源
    • 22
    • 9
    • 1
    HEK-293 Cells
    标记
    This IFNA protein is labelled with His tag.
    原理
    Cynomolgus IFN alpha/beta R2 Protein
    序列
    Ile27-Lys243
    产品特性
    Recombinant Cynomolgus IFN alpha/beta R2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile27-Lys243.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 70.28 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IFNA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IFNA (Interferon alpha (IFNA))
    别名
    IFN alpha (IFNA 产品)
    别名
    IFN-alphaO Protein, IFN-ALPHA-1 Protein, IFN1@ Protein, Ifa Protein, Ifa8 Protein, interferon alpha 16 Protein, interferon, alpha 1 Protein, interferon alpha Protein, interferon-alpha Protein, IFNA16 Protein, IFNA1 Protein, Ifna Protein, IFNA Protein
    背景
    Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well.
    分子量
    25.93 kDa. Due to glycosylation, the protein migrates to 43-60 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling, TLR signaling, Hepatitis C, Inflammasome
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