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VSIG4 Protein (AA 20-283) (His tag)

VSIG4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275843
发货至: 中国
  • 抗原 See all VSIG4 蛋白
    VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
    蛋白类型
    Recombinant
    产品特性
    AA 20-283
    宿主
    • 9
    • 3
    • 1
    资源
    • 8
    • 3
    • 1
    • 1
    HEK-293 Cells
    标记
    This VSIG4 protein is labelled with His tag.
    原理
    Human VSIG4 Protein
    序列
    Arg20-Pro283
    产品特性
    Recombinant Human VSIG4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg20-Pro283.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
    别名
    VSIG4 (VSIG4 产品)
    别名
    DKFZp468O0322 Protein, CRIg Protein, Z39IG Protein, A530061A11 Protein, BC025105 Protein, V-set and immunoglobulin domain containing 4 Protein, VSIG4 Protein, Vsig4 Protein
    背景
    VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of the B7 family. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.
    分子量
    30.3 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
    NCBI登录号
    NP_009199
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