VSIG4 Protein (His tag,Fc Tag)
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- 抗原 See all VSIG4 蛋白
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This VSIG4 protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Mouse VSIG4 Protein (His & Fc Tag)
- 序列
- Met 1-Pro 187
- 产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Pro 187) of mouse VSIG4 (NP_808457.1) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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- Discover our top product VSIG4 蛋白
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V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) (AA 20-283) protein (His tag)
VSIG4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) (AA 25-288) protein (His tag)VSIG4 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) protein (His tag)VSIG4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) (AA 20-283) protein (His tag)Crystallography grade VSIG4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4) (AA 20-399) protein (rho-1D4 tag)Crystallography grade VSIG4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- VSIG4 (V-Set and Immunoglobulin Domain-Containing Protein 4 (VSIG4))
- 别名
- VSIG4 (VSIG4 产品)
- 别名
- DKFZp468O0322 Protein, CRIg Protein, Z39IG Protein, A530061A11 Protein, BC025105 Protein, V-set and immunoglobulin domain containing 4 Protein, VSIG4 Protein, Vsig4 Protein
- 背景
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Background: VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. No VSIG4 expression appears to be present in T and B cells. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. Mouse VSIG4 is synthesized as a 280 amino acid precursor that contains a signal sequence, an V-type I g domain (aa 36-115), one potential N-linked glycosylation site, and a single transmembrane domain. The V-type I g domain of mouse VSIG4 shares 86% and 80% aa sequence identity with the V-type I g domains of rat and human VSIG4, respectively.
Synonym: A530061A11;BC025105;CRIg;Z39IG
- 分子量
- 47 kDa
- NCBI登录号
- NP_808457
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