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FLT4 Protein (AA 25-776) (His-Avi Tag)

FLT4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275839
发货至: 中国
  • 抗原 See all FLT4 蛋白
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    蛋白类型
    Recombinant
    产品特性
    AA 25-776
    宿主
    • 20
    • 5
    • 3
    • 2
    资源
    • 14
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This FLT4 protein is labelled with His-Avi Tag.
    原理
    Human VEGF R3/FLT4 Protein
    序列
    Tyr25-Ile776
    产品特性
    Recombinant Human VEGF R3/FLT4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Tyr25-Ile776.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.29 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product FLT4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    别名
    VEGF R3 (FLT4 产品)
    别名
    FLT41 Protein, LMPH1A Protein, PCL Protein, VEGFR3 Protein, AI323512 Protein, Chy Protein, Flt-4 Protein, VEGFR-3 Protein, Vegfr3 Protein, cb1059 Protein, fms related tyrosine kinase 4 Protein, FMS-like tyrosine kinase 4 Protein, fms-related tyrosine kinase 4 Protein, FLT4 Protein, Flt4 Protein, flt4 Protein
    背景
    Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery.
    分子量
    87.4 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result.
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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