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TYRO3 Protein (AA 41-427) (His tag)

TYRO3 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
产品编号 ABIN7275812
发货至: 中国
  • 抗原 See all TYRO3 蛋白
    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
    蛋白类型
    Recombinant
    产品特性
    AA 41-427
    宿主
    • 17
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    资源
    • 8
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This TYRO3 protein is labelled with His tag.
    原理
    Cynomolgus TYRO3 Protein
    序列
    Gly41-Ser427
    产品特性
    Recombinant Cynomolgus TYRO3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly41-Ser427.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TYRO3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
    别名
    TYRO3 (TYRO3 产品)
    别名
    TYRO3 Protein, brt Protein, byk Protein, dtk Protein, rse Protein, sky Protein, tif Protein, Xksy Protein, MGC145734 Protein, DKFZp469I0432 Protein, LOC100231598 Protein, BYK Protein, Dtk Protein, RSE Protein, Sky Protein, Tif Protein, Brt Protein, REK Protein, ksy Protein, xksy Protein, AI323366 Protein, Etk-2 Protein, Rse Protein, TYRO3 protein tyrosine kinase Protein, TYRO3 protein tyrosine kinase L homeolog Protein, TYRO3 protein tyrosine kinase 3 Protein, TYRO3 Protein, tyro3 Protein, Tyro3 Protein, tyro3.L Protein
    背景
    The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew macrophage polarization towards a pro-tumor M2-like phenotype.In macrophages, the TAM receptors also promote apoptotic cell clearance, a tumor-promoting process called efferocytosis. The TAM receptors bind the "eat-me" signal phosphatidylserine on apoptotic cell membranes using Gas6 and Protein S as bridging ligands.
    分子量
    42.47 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A2K5WCY8
    途径
    RTK signaling
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