DcR1 Protein (AA 24-236) (His tag)
TNFRSF10C
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- 抗原 See all DcR1 (TNFRSF10C) 蛋白
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-236
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This DcR1 protein is labelled with His tag.
- 原理
- Human DcR1/TRAILR3 Protein
- 序列
- Tyr24-Ala236
- 产品特性
- Recombinant Human DcR1/TRAILR3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr24-Ala236.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.57 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 1-259) protein (GST tag)
TNFRSF10C 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) proteinTNFRSF10C 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- 别名
- DcR1 (TNFRSF10C 产品)
- 别名
- CD263 Protein, DCR1 Protein, DCR1-TNFR Protein, LIT Protein, TRAIL-R3 Protein, TRAILR3 Protein, TRID Protein, TNFRSF10C Protein, TNF receptor superfamily member 10c Protein, TNFRSF10C Protein
- 背景
- The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family, which mediates apoptosis by the extrinsic pathway. Up-regulation of decoy receptors, DcR1 and DcR2, may result in diminished binding of TRAIL to their functional receptors. DcR1 expression occurs in a subset of EC and may contribute to resistance to TRAIL-induced apoptosis.
- 分子量
- 23.5 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.
- UniProt
- Q05D71
- 途径
- Apoptosis
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