SIGLEC10 Protein (AA 17-552) (His tag)
-
- 抗原 See all SIGLEC10 蛋白
- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
- 蛋白类型
- Recombinant
- 产品特性
- AA 17-552
-
宿主
- Cynomolgus
-
资源
- HEK-293 Cells
- 标记
- This SIGLEC10 protein is labelled with His tag.
- 原理
- Cynomolgus Siglec-10 Protein
- 序列
- Thr17-Asn552
- 产品特性
- Recombinant Cynomolgus Siglec-10 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Asn552.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus Siglec-10, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Siglec-10 Antibody, hFc Tag with the EC50 of 42.0ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product SIGLEC10 蛋白
-
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 17-546) protein (His tag)
SIGLEC10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) protein (Fc-Avi Tag,Biotin)SIGLEC10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Arg119Ala-Mutant) protein (His-Avi Tag,Biotin)SIGLEC10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 17-546) protein (His-Avi Tag,Biotin)SIGLEC10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 17-546) protein (Fc-Avi Tag)SIGLEC10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Arg119Ala-Mutant) protein (His-Avi Tag)SIGLEC10 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Active) protein (mFc Tag)SIGLEC10 宿主: 人 宿主: 人细胞 Recombinant >90 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Active) protein (Fc Tag)SIGLEC10 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Active) protein (Biotin)SIGLEC10 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) protein (Fc Tag)SIGLEC10 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in 25 mM MES, 150 mM NaCl, 0.5M Arginine ( pH 5.0).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
- 别名
- Siglec-10 (SIGLEC10 产品)
- 别名
- PRO940 Protein, SIGLEC-10 Protein, SLG2 Protein, Siglecg Protein, SIGLEC10 Protein, slg2 Protein, pro940 Protein, siglec-10 Protein, sialic acid binding Ig like lectin 10 Protein, sialic acid binding Ig-like lectin 10 Protein, sialic acid-binding Ig-like lectin 10 Protein, SIGLEC10 Protein, Siglec10 Protein, LOC484343 Protein, LOC100066644 Protein, siglec10 Protein, LOC100513863 Protein, LOC100340374 Protein
- 背景
- Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
- 分子量
- 59.90 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WBX8
-
