RGMA Protein (AA 48-422) (His-Avi Tag,Biotin)
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- 抗原 See all RGMA 蛋白
- RGMA (RGM Domain Family, Member A (RGMA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 48-422
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This RGMA protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Human RGMa Protein
- 序列
- Cys48-Gly422
- 产品特性
- Recombinant Biotinylated Human RGMa Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Cys48-Gly422.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product RGMA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- RGMA (RGM Domain Family, Member A (RGMA))
- 别名
- RGMa (RGMA 产品)
- 别名
- RGM Protein, BC059072 Protein, C230063O06 Protein, repulsive guidance molecule family member a Protein, repulsive guidance molecule family member A Protein, RGMA Protein, Rgma Protein
- 背景
- Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS).
- 分子量
- 44.5 kDa. Due to glycosylation, the protein migrates to 45-48 kDa based on Tris-Bis PAGE result.
- 途径
- Tube Formation
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