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RGMA Protein (His-Avi Tag)

RGMA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
产品编号 ABIN7275513
发货至: 中国
  • 抗原 See all RGMA 蛋白
    RGMA (RGM Domain Family, Member A (RGMA))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 1
    • 1
    • 1
    资源
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This RGMA protein is labelled with His-Avi Tag.
    序列
    Cys48-Gly422
    纯度
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    RGMA (RGM Domain Family, Member A (RGMA))
    别名
    RGMa (RGMA 产品)
    别名
    RGM Protein, BC059072 Protein, C230063O06 Protein, repulsive guidance molecule family member a Protein, repulsive guidance molecule family member A Protein, RGMA Protein, Rgma Protein
    背景
    RGMA, RGM,Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS).  RGM is expressed in pathogenic Th17 cells and induces neurodegeneration by binding to neogenin.
    分子量
    44.5 kDa. Due to glycosylation, the protein migrates to 45-48 kDa based on Tris-Bis PAGE result.
    途径
    Tube Formation
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