PLAU Protein (AA 21-431) (His-Avi Tag,Biotin)
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- 抗原 See all PLAU 蛋白
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-431
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PLAU protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Human PLAU/uPA Protein (active form)
- 序列
- Ser21-Leu431
- 产品特性
- Recombinant Biotinylated Human PLAU/uPA Protein (active form) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser21-Leu431, which consists of two chains: Long chain A (Ser21-Phe177) and chain B (Ile179-Leu 431). The long chain A is further cleaved to yield a short chain A (Lys156-Phe 177) and N-Terminus fragment (Ser21-Lys155).
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human uPAR, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human PLAU, His Tag with the EC50 of 13.6ng/ml determined by ELISA. See testing image for detail.
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Plasminogen Activator, Urokinase (PLAU) (AA 21-431) protein (His tag)
PLAU 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Plasminogen Activator, Urokinase (PLAU) (AA 21-430) protein (His tag)PLAU 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Plasminogen Activator, Urokinase (PLAU) (AA 179-298) protein (His-IF2DI Tag)PLAU 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Plasminogen Activator, Urokinase (PLAU) (AA 16-115) protein (GST tag)PLAU 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Plasminogen Activator, Urokinase (PLAU) (AA 179-431) protein (His tag)Crystallography grade PLAU 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Plasminogen Activator, Urokinase (PLAU) (AA 21-177) protein (His tag)Crystallography grade PLAU 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Plasminogen Activator, Urokinase (PLAU) (AA 21-431) protein (His tag)Crystallography grade PLAU 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- 别名
- PLAU (PLAU 产品)
- 别名
- PLAU Protein, u-PA Protein, ATF Protein, BDPLT5 Protein, QPD Protein, UPA Protein, URK Protein, uPA Protein, UPAM Protein, plasminogen activator, urokinase Protein, urokinase-type plasminogen activator Protein, PLAU Protein, CpipJ_CPIJ002131 Protein, CpipJ_CPIJ006543 Protein, CpipJ_CPIJ013396 Protein, CpipJ_CPIJ013623 Protein, Plau Protein
- 背景
- Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
- 分子量
- 49.3 kDa. Due to protein lysis and glycosylation, the protein migrates to 24-26 kDa(long chain A), 35-38 kDa(chain B) and 52-60 kDa(long chain A&chain B) based on Tris-Bis PAGE result.
- 途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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