PD-L1 Protein (AA 19-238) (Fc Tag)
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- 抗原 See all PD-L1 蛋白
- PD-L1 (CD274 (PD-L1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-238
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This PD-L1 protein is labelled with Fc Tag.
- 原理
- Cynomolgus PD-L1/B7-H1 Protein
- 序列
- Phe19-Arg238
- 产品特性
- Recombinant Cynomolgus PD-L1/B7-H1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe19-Arg238.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus PD-L1, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-PD-L1 Antibody, hFc Tag with the EC50 of 10.0ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product PD-L1 蛋白
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CD274 (PD-L1) (AA 19-238) protein (Fc Tag)
PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) protein (His tag)PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) protein (His-Avi Tag,Biotin)PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) protein (His tag)PD-L1 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) protein (mFc Tag)PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) (Active) protein (His tag)HPLC verified PD-L1 宿主: 人 宿主: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. Active
CD274 (PD-L1) (AA 19-237) protein (Fc Tag)PD-L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) protein (His tag)PD-L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) protein (His tag,Biotin)PD-L1 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD274 (PD-L1) (AA 19-238) protein (His tag,Biotin)PD-L1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PD-L1 (CD274 (PD-L1))
- 别名
- PD-L1 (PD-L1 产品)
- 别名
- B7-H Protein, B7H1 Protein, PD-L1 Protein, PDCD1L1 Protein, PDCD1LG1 Protein, PDL1 Protein, A530045L16Rik Protein, B7h1 Protein, Pdcd1l1 Protein, Pdcd1lg1 Protein, Pdl1 Protein, RGD1566211 Protein, CD274 molecule Protein, CD274 antigen Protein, programmed cell death 1 ligand 2 Protein, CD274 Protein, Cd274 Protein, PDCD1LG2 Protein
- 背景
- B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.
- 分子量
- 52 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- UniProt
- G7PSE7
- 途径
- Cancer Immune Checkpoints
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