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PD-1 Protein (AA 25-167) (Fc Tag)

This Recombinant PD-1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7275423
发货至: 中国

Quick Overview for PD-1 Protein (AA 25-167) (Fc Tag) (ABIN7275423)

抗原

See all PD-1 (PDCD1) 蛋白
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

蛋白类型

Recombinant

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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 25-167

    标记

    This PD-1 protein is labelled with Fc Tag.

    原理

    Mouse PD-1/PDCD1 Protein

    序列

    Leu25-Gln167

    产品特性

    Recombinant Mouse PD-1/PDCD1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu25-Gln167.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    The affinity constant of 0.15μM as determined in SPR assay (Biacore T200). See testing image for detail.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    PD-1

    背景

    Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.

    分子量

    42.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

    NCBI登录号

    NP_032824

    途径

    Cancer Immune Checkpoints
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