NCR3 Protein (AA 19-138) (Fc Tag)
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- 抗原 See all NCR3 蛋白
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-138
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NCR3 protein is labelled with Fc Tag.
- 原理
- Human NKp30/NCR3/CD337 Protein
- 序列
- Leu19-Thr138
- 产品特性
- Recombinant Human NKp30/NCR3/CD337 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu19-Thr138.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human NKp30, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-NKp30 Antibody, hFc Tag with the EC50 of 13.4ng/ml determined by ELISA. The affinity constant of 23.10 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Discover our top product NCR3 蛋白
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Natural Cytotoxicity Triggering Receptor 3 (NCR3) protein (His-Avi Tag)
NCR3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-138) protein (His-Avi Tag,Biotin)NCR3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (His-DYKDDDDK-Strep II Tag)NCR3 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 1-201) protein (GST tag)NCR3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (His tag)Crystallography grade NCR3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-201) protein (rho-1D4 tag)Crystallography grade NCR3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Natural Cytotoxicity Triggering Receptor 3 (NCR3) (AA 19-135) protein (Fc Tag)NCR3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- 别名
- NKp30 (NCR3 产品)
- 别名
- MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
- 背景
- NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
- 分子量
- 39.8 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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