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NCR3 Protein (His tag)

NCR3 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318807
发货至: 中国
  • 抗原 See all NCR3 蛋白
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    蛋白类型
    Recombinant
    宿主
    • 21
    • 2
    • 1
    • 1
    • 1
    资源
    • 13
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This NCR3 protein is labelled with His tag.
    原理
    Recombinant Human NCR3/NKp30 Protein (His Tag)
    序列
    Leu19-Thr138
    产品特性
    Recombinant Human Natural Cytotoxicity Triggering Receptor 3 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr138 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NCR3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    别名
    NCR3/NKp30 (NCR3 产品)
    别名
    MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
    背景

    Background: Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed ""Natural Cytotoxicity Receptors"". They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.

    Synonym: Natural Cytotoxicity Triggering Receptor 3, Activating Natural Killer Receptor p30, Natural Killer Cell p30-Related Protein, NK-p30, NKp30, CD337, NCR3, 1C7, LY117,1C7,DAAP-90L16.3,MALS

    分子量
    12.8 kDa
    UniProt
    O14931
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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