nectin-3 Protein (AA 58-400) (His-Avi Tag,Biotin)
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- 抗原 See all nectin-3 (NECTIN3) 蛋白
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 58-400
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This nectin-3 protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Human Nectin-3/CD113 Protein
- 序列
- Gly58-Asp400
- 产品特性
- Recombinant Biotinylated Human Nectin-3/CD113 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly58-Asp400.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.13 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Discover our top product NECTIN3 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in 20 mM PB, 250 mM NaCl ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- 别名
- Nectin-3 (NECTIN3 产品)
- 背景
- The Nectin family has at least four members (Nectin-1-4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein.
- 分子量
- 40.6 kDa. Due to glycosylation, the protein migrates to 68-82 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9NQS3-1
- 途径
- Cell-Cell Junction Organization
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