MUC16 Protein (AA 12660-12923) (His-Avi Tag,Biotin)
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- 抗原 See all MUC16 (CA125) 蛋白
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- 蛋白类型
- Recombinant
- 产品特性
- AA 12660-12923
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MUC16 protein is labelled with His-Avi Tag,Biotin.
- 原理
- Biotinylated Human CA125/MUC16 Protein
- 序列
- Gly12660-Met12923
- 产品特性
- Recombinant Biotinylated Human CA125/MUC16 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly12660-Met12923.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human MSLN, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human CA125, His Tag with the EC50 of 0.35μg/ml determined by ELISA. See testing image for detail.
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- Discover our top product CA125 蛋白
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Mucin 16, Cell Surface Associated (CA125) (AA 12660-12923) protein (His-Avi Tag)
CA125 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Mucin 16, Cell Surface Associated (CA125) (AA 1321-1415) protein (GST tag)CA125 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mucin 16, Cell Surface Associated (CA125) (Active) protein (His tag)CA125 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Mucin 16, Cell Surface Associated (CA125) protein (Biotin)CA125 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Mucin 16, Cell Surface Associated (CA125) (AA 12660-12923) protein (Fc Tag,AVI tag,Biotin)CA125 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- 别名
- CA125 (CA125 产品)
- 别名
- CA125 Protein, 1110008I14Rik Protein, Ca125 Protein, Gm1480 Protein, RGD1308422 Protein, MUC16 Protein, mucin 16, cell surface associated Protein, mucin 16 Protein, mucin-16 Protein, MUC16 Protein, Muc16 Protein, LOC476718 Protein, LOC712735 Protein
- 背景
- MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.
- 分子量
- 31.3 kDa. Due to glycosylation, the protein migrates to 52-80 kDa based on Tris-Bis PAGE result.
- UniProt
- Q8WXI7
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